(NSAID) of the coxib class used to control pain and inflammation associated with osteoarthritis in horses. For use in horses only. The safety of Equioxx has not been determined in horses less than one year of age or in breeding horses, pregnant or lactating mares. Appropriate laboratory tests should be conducted to establish hematological and serum biochemical baseline data before and periodically during administration of any NSAID. side effects of Equioxx can include sores or ulcers on the tongue, lips, and skin of the mouth and face. Always provide the Client Information Sheet with the prescription.
Consider appropriate washout times when switching from one NSAID to another NSAID or corticosteroid. Change in behavior (such as increased or decreased activity level). Other common NSAIDs for horses are phenylbutazone (bute) and Banamine (flunixin meglumine). Great product for my horse that suffers from Navicular. To deliver the correct dose, round the horse's body weight up to the nearest 50 pound increment (if the body weight is an exact 50 pound increment, do not round up). Merial LLC, Duluth, GA 30096-4640. If you liked this blog, please subscribe below, and share it with …
Your veterinarian may want to check that all of your horse's medicines can be given together. Equioxx is an NSAID and requires a prescription from your veterinarian. The safe use of Equioxx Oral Paste in horses less than one year in age, horses used for breeding, or in pregnant or lactating mares has not been evaluated. The concomitant use of protein-bound drugs with Equioxx hasn't been studied in horses. The most common
Horses that have experienced adverse reactions from one NSAID may experience adverse reactions from another NSAID. Two hundred forty horses were evaluated for effectiveness and 252 horses were evaluated for safety. Clients should be advised to observe for signs of potential drug toxicity and be given a Client Information Sheet with each prescription. therapy?
®Equioxx is a registered trademark of Merial. With the establishment of comparable relative bioavailability, the field studies conducted with Equioxx Oral Paste are therefore applicable in establishing the effectiveness of the tablet formulation as well. There were no other drug-related adverse findings in this study. Tell your veterinarian about all medications that you have given your horse in the past, and any medications you are planning to give with Equioxx paste. Treatment administrators and caretakers should be aware of the potential for adverse reactions and the clinical signs associated with NSAID intolerance. Equioxx can be given with or without food. In a target animal safety study, firocoxib was administered orally to healthy adult horses (two male castrates and four females per group) at 0, 0.1, 0.3 and 0.5 mg firocoxib/kg body weight (1, 3 and 5× the recommended dose) for 30 days.
Clinical chemistry and coagulation abnormalities were seen in several horses in the 0.5 mg/kg (5×) group. Clients should be advised to observe for signs of potential drug toxicity and be given a Client Information Sheet with each prescription. Other medical problems or allergies that your horse has now, or has had in the past. Generic Name: firocoxib paste Many times, equine NSAIDs are only used once a day for convenience or due to medication testing compliance. Do not use in horses intended for human consumption. Equioxx (firocoxib) Oral Paste was safely used concomitantly with other therapies, including vaccines, anthelmintics, and antibiotics, during the field studies. Patients at greatest risk for adverse events are those that are dehydrated, on diuretic therapy, or those with existing renal, cardiovascular, and/or hepatic dysfunction. Always provide the Client Information Sheet with the prescription. You should read this information before you start giving your horse Equioxx paste and review it each time your prescription is refilled. We will continue purchasing it.
See Information for Owner or Person Treating Horse section of this package insert. One syringe can treat a horse up to 1,250 lbs. Gross and microscopic lesions of the kidneys consistent with tubulointerstitial nephropathy were seen in all treated groups. Administration of firocoxib at 0.3 and 0.5 mg/kg body weight was associated with an increased incidence of oral ulcers as compared to the control group but, no oral ulcers were noted with 0.1 mg/kg. As a class, cyclooxygenase inhibitory NSAIDs may be associated with renal and gastrointestinal toxicity. Non-steroidal Horses treated with Equioxx showed improvement in veterinarian-assessed lameness, pain on manipulation, range of motion, and joint swelling that was comparable to the active control. Reviewing the company, not the product-----Entirely Pets has been efficient, professional, helpful and has provided excellent customer service for multiple purchases that we have made.
Horses may have experienced more than one of the observed adverse reactions during the study. Has previously had an allergic reaction (such as hives, facial or lower limb swelling, or red or itchy skin) to aspirin or other NSAIDs. Do not double dose. This study demonstrated comparative relative bioavailability between the two formulations therefore establishing the same relative effectiveness of the tablet formulation as the paste formulation in horses. In addition, several 12.5X horses had elevated liver enzymes (GGT, SDH, AST and ALT). Prove in both field and laboratory trials to be safe at the recommended dose. Injection site changes characterized by inflammatory cell influx and rarely tissue necrosis were seen in all study groups including the control group.
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